Edit: The answer is, "Not Very". 3-D Secure is not very well received, many of us who opted in have since opted out.
MasterCard Secure Code was used by my bank for my debit card. It was an opt in program and I discovered that opting in was a mistake. I forgot the password I set and instead of a 5 minute online transaction, it turned into a 2 hour transaction as I blundered around looking for how to reset the password. My opinion is that we will see NFC based payments grow before multi factor authentication based credit cards, since phones already have the ability to do multifactor authentication on credit card transactions. ApplePay, when it's available, is very convenient, and uses biometric authentication.